The protective properties of active vitamin D3 metabolite did not depend on the complexes used for nanoparticle stabilization, while both of them statistically significantly suppressed nitric oxide release increased by LPS treatment Fig. Travis J. Hippocampal slices were transferred to 1. Thus, different tests and finally these multiparameter outcomes may provide an accurate and complete assessment of the vital status of hippocampal organotypic slices Cho et al. Roy T. Each coach—participant pair had a 45—60 minute initial phone or in-person meeting followed by weekly phone meetings over next 2 months and then monthly meetings over the last 8 months. Discussion This study presents data from a pragmatic cluster-randomized effectiveness ENCOURAGE trial of the peer coaching intervention, conducted among diabetic, mostly African American participants in rural Alabama with limited access to medical resources. Diabetes Educ. In another study of patients with diabetes and comorbid emotional disorders, peer education intervention reduced anxiety, depression and distress and improved self-management skills and quality of life .
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It was considered as the most favorable when the zeta potential reached the constant value close to the value of the free polyelectrolyte in the solution.
Both intervention- and control-arm participants received a one hour group diabetes education class at enrollment covering basics of diabetes and its self-management emphasizing healthy eating and physical activity; stress reduction; and visits to the doctor . This analytic method allowed potential differential intervention effects over time to emerge, and suggested that intervention effects may be greatest after 15 months, a possibility supported by the fact that peer coaches and participants often continued their relationships well beyond the conclusion of the study.
Safford M. Neuroendocrine link between stress, depression and diabetes. D3-loaded nanocapsules were synthesized as described above except that prior to the emulsification process, calcitriol was dissolved in the AOT-in-chloroform solution 0.
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|In the next set of experiments, we evaluated the neuroprotective property of active form of vit.
Front Neuroendocrinol — Contacts were focused on selecting individualized self-management goals and providing coaching on how to achieve the goals. Psychological and pharmacological interventions for depression in patients with diabetes mellitus and depression. Epidemiology of depression and diabetes: a systematic review. Our findings underlined that the neuroprotective action of vitamin D3 in both free and nanoparticle forms seems to be related to the suppression of LPS-induced nitric oxide release.
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Volunteer peer support, diabetes, and depressive symptoms Results from the ENCOURAGE trial
Play next; Play now. Semantic Scholar profile for Jan Detka, with fewer than 50 highly influential citations. +7 authors Bogusława Budziszewska; Neurotoxicity Research; Gieryn Katarzyna, Jan Detka, Monika Leœkiewicz, Magdalena Regulska, Marta.
The study was a cluster RCT with the initial plan calling for randomization of medical practices to either the intervention or control arm.
Telephone-based mutual peer support for depression: a pilot study. All measurements were performed in 0. LPS is a primary component of endotoxin from Gram-negative bacteria cell walls Kettenmann et al.
The beneficial influence of calcitriol on the changes caused by bacterial endotoxin should be emphasized. Roy T.
The follow-up time for this study was extended from the initially planned 12—15 months to maximize follow-up data collection and to accommodate community members who wanted to provide follow-up data, concordant with the community-engaged research framework .
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|Different times between baseline and follow-up data collection shorter for some participants vs.
Therefore, recently the role of NO as an important regulator in neurodegenerative processes is discussed Kiemer et al. This ability of 1,dihydroxyvitamin D3 may be linked to strongly postulated neuroprotective properties of the secosteroid. Statistical analysis was performed using Statistica Cho S, Wood A, Bowlby MR Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics.
effect of the prenatal stress procedure on the serum insulin level (Detka et al., ).
Jan Detka of Polish Academy of Sciences, Warsaw (PAN) | Read 31 publications, and contact Jan Detka on ResearchGate, the professional network for scientists. S. Karger AG, Basel. View. Monika Majewska-Szczepanik; [ ].
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34, Monika Detka / Aleksandra Nowacka, Poland. 37, Stina Karlsson / Hedvig Simme, Sweden. 37, Kim Germ / Eva Hlebec, Slovenia.
37, Lynn Musschoot / Jana.
Therefore, we selected them for our comparative study regarding the protective effect of free calcitriol and calcitriol-loaded nanoparticles. On the other hand, systemic vitamin D3 treatment carries the risk of undesirable effects, e.
We hypothesized that, compared with usual care, the peer support intervention would decrease depressive symptoms and would have greater effects among participants with depressive symptoms than among those without depressive symptoms, namely greater improvements in glycosylated hemoglobin A1c HbA1cbody mass index BMI and health related quality of life QoL. Control slices were treated with vehicle PBS buffer.
Recent systematic reviews found that psychological interventions focused on depressive symptoms in individuals with diabetes may have reduced depressive symptoms, but did not improve glycemic control . All chemicals were used without further purification.